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3-hexanoyl-NBD Cholesterol

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    3-<wbr/>hexanoyl-<wbr/>NBD Cholesterol
  • 3-<wbr/>hexanoyl-<wbr/>NBD Cholesterol
Cat No: 13221
Chemicals - Api/drug/substrate/ Analytical Standard
Cayman
€90.00
Price is excluding VAT and does not include packaging neither shipping

A fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to carbon 3, at the hydrophilic end of cholesterol, separated by a 6-carbon spacer; allows the cholesterol to properly orient in membrane bi-layers while the fluorescent t...

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Territorial Availability: Available through Bertin Pharma only in Europe
Product Overview:
A fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to carbon 3, at the hydrophilic end of cholesterol, separated by a 6-carbon spacer; allows the cholesterol to properly orient in membrane bi-layers while the fluorescent tag is presented outside of the bi-layer
3-hexanoyl-NBD-Cholesterol is a fluorescently-tagged cholesterol derivative with the hydrophilic NBD fluorophore attached to carbon 3, at the hydrophilic end of cholesterol, separated by a 6-carbon spacer. This design allows the cholesterol to properly orient in membrane bilayers while the fluorescent tag is presented outside of the bilayer. This should model the behavior of cholesterol in membranes better than the previously-used 25-NBD cholesterol, which positions NBD directly on the 25th carbon of cholesterol at the hydrophobic terminus. Fluorescently-tagged lipids have been used to study their interactions with proteins, their utilization by cells and liposomes, and for the development of assays for lipid metabolism.
Size: 500 µg
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Label: Fluorescent Probe
CAS Number: 201731-19-3
Molecular Formula: C39H58N4O5
SMILES: [H]N(C1=CC=C([N+]([O-])=O)C2=NON=C12)CCCCCC(O[C@H](C3)CC[C@@]4(C)C3=CC[C@]5([H])[C@]4([H])CC[C@@]6(C)[C@@]5([H])CC[C@]6([H])[C@@](C)([H])CCCC(C)C)=O
Molecular Weight: 662.9
Formulation: A crystalline solid
Purity: ≥98%
Custom Code: 2937903000
UNSPSC code: 12352100

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