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Butenoyl PAF

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    Butenoyl PAF
  • Butenoyl PAF
Cat No: 60929
Chemicals - Lipids / Fatty Acids
Cayman
€84.00
Price is excluding VAT and does not include packaging neither shipping

A product of the oxidative decomposition of 2-arachidonoyl phospholipids; 10-fold less potent than PAF as a PAF receptor agonist, but present in amounts 100-fold greater,
Butenoyl and butanoyl PAF are both products of the oxidative decomposition of 2-a...

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Territorial Availability: Available through Bertin Pharma only in Europe
Product Overview:
A product of the oxidative decomposition of 2-arachidonoyl phospholipids; 10-fold less potent than PAF as a PAF receptor agonist, but present in amounts 100-fold greater,
Butenoyl and butanoyl PAF are both products of the oxidative decomposition of 2-arachidonoyl phospholipids. Oxygenation of C-5 of the 5,6 double bond followed by cleavage of the hydroperoxide results in a PAF-like compound with a 4-carbon residue esterified in the sn-2 position; similar oxidized lipid products also act as ligands for oxidized lipid receptors and peroxisome proliferator-activated receptor. Although butenoyl PAF is 10-fold less potent than PAF as a PAF receptor agonist, it is present in amounts 100-fold greater than enzymatically generated PAF. Therefore, oxidation of LDL phospholipids generates physiologically relevant bioactive PAF-like molecules.
Size: 1 mg
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 365 days maximum after production
CAS Number: 474944-25-7
Molecular Formula: C28H56NO7P
SMILES: O=C(/C=C/C)O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COCCCCCCCCCCCCCCCC
Molecular Weight: 549.7
Formulation: A solution in ethanol
Purity: ≥98%
Custom Code: 2919905050
UNSPSC code: 12352100
UN Number: UN1170

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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Cross selling for this product : Butenoyl PAF There are 5 products.

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