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BayCysLT2

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    BayCysLT<sub>2</sub>
  • BayCysLT<sub>2</sub>
Cat No: 10532
Chemicals - Prostaglandin/leukotriene/ Thromboxane
Cayman
€73.00
Price is excluding VAT and does not include packaging neither shipping

A potent, selective CysLT2 receptor antagonist that inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively
The cysteinyl leukotrienes LTC4 and LTD4 are potent mediators of asthm...

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Territorial Availability: Available through Bertin Pharma only in Europe
Product Overview:
A potent, selective CysLT2 receptor antagonist that inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively
The cysteinyl leukotrienes LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of G-protein coupled receptors, CysLT1 and CysLT2. BayCysLT2 is a potent CysLT2 receptor antagonist that inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. BayCysLT2 concentration-dependently reverses LTC4-stimulated perfusion pressure increase and contractility decrease in isolated Langendorff-perfused guinea pig hearts.
Size: 1 mg
Shipping: wet ice
Stability: Store at -20 degrees; shelf life 730 days maximum after production
CAS Number: 712313-33-2
Molecular Formula: C34H39NO8
SMILES: O=C(NC1CCCC(C(O)=O)C1)C2=CC(C(O)=O)=CC=C2OCCCC(C=C3)=CC=C3OCCCCOC4=CC=CC=C4
Molecular Weight: 589.7
Formulation: A crystalline solid
Purity: ≥95%
Custom Code: 2916310002
UNSPSC code: 12352100

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