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Kaempferol - NF-κB

NF-κB
Reference 11852
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Data

CAS number
520-18-3
Molecular Formula
C15H10O6
Formulation
A crystalline solid
Purity
≥98%
Lambda Max
204, 267, 368 nm
Stability
2 years
Storage
-20°C
Shipping
Wet ice
Correlated Keywords
14461-95-1, indigo, yellow, kaempherol, kampcetin, kempferol, pelargidenolon, populnetin, rhamnolutin, robigenin, flavonoids, antioxidants, inflammation, receptors, signalings, angiogenesis, tyrosine, kinases, plants, leaves, estrogen, agonists, inverse, anti-oxidants, oxidants, glycation, endproduct, signallings, VEGF, EGFR, HGF, NSC407289, NSC-407289, NSC656277, NSC-656277

Description

Kaempferol is a flavonoid which is abundant in a variety of plant leaves and fruits. It has diverse physiological activities through both direct and indirect effects. For example, kaempferol directly binds estrogen receptors α and β, acting as an inverse agonist or agonist. It also acts as an antioxidant, which presumably contributes to its ability to suppress advanced glycation endproduct-induced NADPH oxidase, NF-κB signaling, and hypoxia-inducible factor-related angiogenesis and VEGF expression. Kaempferol also suppresses signaling through certain receptor tyrosine kinases, including EGFR and HGF.

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Documentation

Pricing

SizePrice (euros)Quantity  
25 mg48 €
50 mg90 €
100 mg170 €
 
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Kaempferol 19/04/2014