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Ozagrel - Chemicals - Miscellaneous Chemicals

Chemicals.Miscellaneous Chemicals
Reference 70515
Available through Bertin Pharma only in Europe
Product image

Data

CAS number
82571-53-7
Shipping
wet ice
Molecular Formula
C13H12N2O2
Smiles
OC(=O)\C=C/c1ccc(cc1)Cn1ccnc1
Molecular Weight
228.3
Purity
≥98%
Stability
Store at -20 degrees; shelf life 365 days maximum after production
UNSPSC Code
12352100
Synonyms
3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid|OKY-046
Supplied as
A crystalline solid
Description_article
Ozagrel
Code_douanier
2933290000
Related_Products_ref
10155|70510
Correlated Keywords
Atherosclerosis|Hypertension|Biochemicals|Inhibitors|thromboxanes, synthases, inhibitors, inhibits, imidizoles, TXAs, antihypertensive, inhibition, atherosclerosis

Description

A selective inhibitor of TXA synthase (IC50 = 11 nM)|Inhibition of thromboxane synthase (TXAS), especially in human platelets, has been a clinical objective for many years. 1-Alkyl (N-alkyl)-imidazole derivatives have been recognized as TXAS inhibitors since the early 1980s. Ozagrel is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXAS with an IC50 of 11 nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.

Documentation

Pricing

SizePrice (euros)Quantity  
5 mg33 €
10 mg63 €
50 mg268 €
100 mg469 €
 
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Ozagrel 22/12/2014
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