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Ozagrel - Chemicals - Miscellaneous Chemicals

Chemicals.Miscellaneous Chemicals
Reference 70515
Available through Bertin Pharma only in Europe
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Data

CAS number
82571-53-7
Shipping
wet ice
Molecular Formula
C13H12N2O2
Smiles
OC(=O)\C=C/c1ccc(cc1)Cn1ccnc1
Molecular Weight
228.3
Purity
≥98%
Stability
Store at -20 degrees; shelf life 365 days maximum
UNSPSC Code
1.23521E7
Synonyms
3-[4-(1H-imidazol-1-ylmethyl)phenyl]-2E-propenoic acid|OKY-046

Description

A selective inhibitor of TXA synthase (IC50 = 11 nM)|Inhibition of thromboxane synthase (TXAS), especially in human platelets, has been a clinical objective for many years. 1-Alkyl (N-alkyl)-imidazole derivatives have been recognized as TXAS inhibitors since the early 1980s. Ozagrel is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXAS with an IC50 of 11 nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.

Documentation

Pricing

SizePrice (euros)Quantity  
10 mg63 €
 
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Ozagrel 22/10/2014